Emergency crews were called to the one-car crash on interstate 79 just after 11p.m.
That crash happened about halfway between the Edinboro and Saegertown exits.
When crews arrived, they found a car on its side down an embankment, sustaining heavy damage.
Four people were in the car at the time of the crash.
The driver was identified as Kina Cuevas, 40, of McKees Rocks; the other three passengers were children.
No word on the extent of their injuries, however, all four were taken to UPMC Hamot for treatment.
Pennsylvania State Police in Meadville say the woman was traveling Northbound on I-79 at a slow rate of speed with the hazard lights on when the car suddenly left the roadway.
State police in Meadville are currently investigating.
Copyright 2017 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.