That crash happened around 9p.m. on Wednesday night along Route 98 in Hayfield Township in Crawford County.
According to PA State Police in Meadville, a man was traveling South on Route 98 when he left the roadway and struck a tree.
The driver of the truck was unresponsive when police arrived on the scene, but was responsive when medical crews arrived.
He was transported to UPMC Hamot for treatment of a moderate head injury.
Police are continuing to investigate what led to the crash.