That crash happened at the intersection of West 38th Street and Lancaster Road, around 12:30 a.m.
According to police at the scene, a gold vehicle was traveling eastbound on west 38th street when a black car went through the stop sign and hit the eastbound car.
The black car was sent into the side of a house, cracking the foundation, while the gold car ended up in a nearby ditch.
The occupants of the gold car were taken to Saint Vincent Hospital for treatment.
The house sustained only moderate damage to the exterior and interior walls; no one inside the home was injured.
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