Fire crews were called to the 900 block of East 8th Street near East Avenue around midnight Tuesday morning for reports of a structure fire.
Once on scene, firefighters discovered fire on all three floors of the home.
Initial reports indicated that there may be people trapped inside.
First responders did not find anyone before they had to evacuate the building.
A Fire Investigator was called to the scene to help determine a cause.
Here is a look at the aftermath of the fire the following afternoon.